Lipofilling with Stem Cells – A Revolution in Plastic Surgery

What is Lipofilling and Why is it Gaining Popularity?


Lipofilling is a technique that allows contour correction of the face and body using the patient’s own fat tissue. Modern technologies enable fat material to be enriched with stem cells, making the procedure not only cosmetic but also rejuvenating. Unlike synthetic fillers and implants, lipofilling provides a natural, soft result while also improving skin quality.

This method is widely used in plastic surgery for:

  • Restoring lost facial volume (cheeks, lips, chin, nasolabial folds);
  • Breast shape correction and augmentation;
  • Enhancing buttock contours;
  • Rejuvenating hands and décolletage area;
  • Treating post-traumatic and post-surgical tissue defects.

Stem Cells in Lipofilling: Why is it Effective?

Stem cells are biological materials with a unique ability to regenerate. They stimulate tissue renewal, accelerate fat graft survival, and enhance its longevity. As a result:

  • Skin texture improves, becoming more hydrated and elastic;
  • The risk of fat resorption is minimized;
  • Recovery time after surgery is reduced;
  • The overall rejuvenation effect is enhanced.

Thanks to stem cells, lipofilling not only restores volume but also genuinely improves the health of the skin and tissues.

About the Procedure

Where is the fat for lipofilling taken from? The fat is extracted from donor areas of the patient using liposuction. The most common donor sites are the abdomen, thighs, flanks, or lower back. The process is performed under local or general anesthesia, depending on the volume of the procedure.
How is the fat prepared before injection? After extraction, the fat tissue undergoes purification and centrifugation. This removes excess fluid, blood, and damaged cells, leaving only viable fat cells and stem cells that improve skin quality and ensure long-lasting fat graft survival.

How long does the procedure take? On average, lipofilling takes between 1 to 3 hours, depending on the intervention volume.

What technologies are used? Modern lipofilling methods include the use of fat tissue enriched with stem cells. This enhances fat graft survival and boosts the rejuvenating effect, as stem cells stimulate tissue regeneration and improve microcirculation.

Will the results look natural? Yes, since the patient’s own fat tissue is used, lipofilling delivers the most natural results. The skin becomes firmer, and facial and body contours gain smoothness without an artificial augmentation effect.

How much fat can be transferred in one procedure? Depending on the treatment area, between 10 and 300 ml of fat can be transferred. For instance, 10–50 ml is typically needed for the face, while breast augmentation may require up to 300 ml per breast.

Lipofilling or Fillers: Which is Better for Facial Rejuvenation?

Patients looking to correct age-related changes often choose between lipofilling and fillers. Here are the key differences:

  • Longevity. Fillers dissolve within 6–18 months, whereas transferred fat can last for years.
  • Naturalness. Lipofilling uses the body’s own tissue, reducing the risk of allergic reactions.
  • Comprehensive Rejuvenation. Stem cells in lipofilling not only restore volume but also stimulate skin renewal.
  • Cost. Fillers require regular touch-ups, making them less cost-effective than lipofilling in the long run.

Can Breasts Be Enlarged with Lipofilling?

Lipofilling can increase breast size by 0.5–1.5 sizes without implants. This procedure is ideal for those seeking a natural breast enhancement. However, it is not suitable for those who want a significant increase in breast size—in such cases, implants are recommended.

Post-Lipofilling Recommendations from Doctors

For the best results after the procedure, it is important to follow specialist recommendations:

  1. Avoid intense physical activity for 2–4 weeks to prevent fat resorption.
  2. Drink plenty of water – this helps improve microcirculation and speeds up healing.
  3. Wear compression garments (if the procedure was done on the body) to minimize swelling and improve fat graft retention.
  4. Avoid extreme temperature changes in the first few weeks after the procedure.
  5. Avoid smoking – nicotine worsens blood circulation and may reduce fat graft survival.

Advantages of Lipofilling

  • Safety – uses the patient’s own tissue, eliminating the risk of allergy or rejection.
  • Longevity – lasts longer than synthetic fillers.

Lipofilling is an innovative technique that not only reshapes the body but also rejuvenates the skin with stem cells. To find out if this procedure is right for you, schedule a consultation with Globalmedik specialists.

What area do you want to correct with lipofilling?

  • Face (cheekbones, lips, nasolabial folds)
  • Breasts (enlargement, asymmetry correction)
  • Buttocks (enlargement, shape improvement)
  • Hands (rejuvenation, volume restoration)
  • Legs (shins, knees)
  • Other

Considering fat grafting for rejuvenation or plumping?

  • Rejuvenation (correction of age-related changes)
  • Increase in volume (chest, buttocks, other areas)
  • An integrated approach (both rejuvenation and volume increase)
  • Haven't decided yet, need advice

When do you plan to undergo the procedure?

  • In the coming month
  • Within 3-6 months
  • This year, but later
  • I'm just collecting information for now.

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Clinic DR. Cem Berkay SINACI

Clinic DR. Cem Berkay SINACI

10
years of international experience
5
Globalmedik rating

Dr. Cem Berkay Sinacı is a specialist in plastic, reconstructive and aesthetic surgery

Experience in plastic surgery: +10 years

Dr. Cem Berkay Sinacı treats VIP patients from all over the world. Currently, he provides services in his own clinic. Thanks to his view on his field of specialization, patients from Turkey and Europe trust him with their bodies.

Dr. Cem Berkay Sinacı calls his profession a scientific art and his results a work of art that sets him apart from others. His priority is the comfort and safety of his patients, so he has developed unique plastic surgery techniques.

Since 2021, he has been providing services in his own clinic.

 

 

 

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Clinic DR. CELAL ALİOĞLU

Clinic DR. CELAL ALİOĞLU

98%
happy patients
100%
result

Private clinic of aesthetic medicine. Situated in the Asian part of the city on the northern shore of the Sea of ​​Marmara. In the clinic you will find not only high-quality service, highly qualified specialists, but also a wonderful, warm welcome to guests (patients).

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Clinic Guler Gamze Eren (Dr. GÜLER GAMZE EREN)

Clinic Guler Gamze Eren (Dr. GÜLER GAMZE EREN)

98 %
satisfied patients
24
patient support hours

Private clinic of aesthetic medicine. Situated in the Asian part of the city on the northern shore of the Sea of ​​Marmara. In the clinic you will find not only high-quality service, highly qualified specialists, but also a wonderful, warm welcome to guests (patients).

 

Read more
Dr.Ayaz Aslan Clinic

Dr.Ayaz Aslan Clinic

23
successful practice
5600+
happy patients

The clinic is located in the luxury district of Istanbul – Nispetiye, which is considered the financial center of Istanbul. For pleasant shopping, the location is suitable.

DIRECTIONS

– surgical facial aesthetics – deep plane smas lift, blepharoplasty, temporal brow lift, transconjunctival midface lift
– rhinoplasty
– mammoplasty
– facial cosmetology

 

 

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