Ozaki Method for Aortic Valve Replacement: Specifics of the Procedure | GlobalMedik

Unique Ozaki Method for Aortic Valve Replacement

Make a short summary of this publication

Lyudmila, 65 years old, faced a serious illness – aortic valve defect. This meant that even minimal physical activity, such as climbing to the 4th floor, walking with grandchildren or going shopping, caused shortness of breath and irregular heartbeat.

What treatments exist?

For such patients, standard medicine offers two options:

  1. Biological prosthesis. However, it has a limited service life and requires repeated operations after 10-15 years.
  2. Mechanical prosthesis. Durable, but requires lifelong blood thinning medication, which entails a number of limitations, especially for women of childbearing age.

These shortcomings have spurred the development of a new approach, the Ozaki method, named after its creator, Japanese surgeon Shigeyuki Ozaki.

What is the Ozaki method?

The Ozaki method is an innovative aortic valve replacement procedure developed by Japanese cardiac surgeon Shigeyuki Ozaki, based on replacing the diseased aortic valve using the patient’s own pericardial tissue (the outer lining of the heart). This eliminates the need to use artificial materials and makes the restoration as natural as possible. In other words, the essence of the method is to use the patient’s own pericardium to create new aortic valve cusps, which ensures high biocompatibility and eliminates the need for lifelong anticoagulants. Advantages of the Ozaki method:

  1. No need for anticoagulants. The patient no longer needs to take blood thinners.
  2. No repeat surgeries. A valve made from the patient’s own tissue lasts much longer, which is especially important for children and young patients.
  3. An ideal solution for women. The method is suitable for young mothers who are contraindicated in taking anticoagulants during pregnancy.
  4. Suitable for an active lifestyle. The load on the heart is reduced even during intense physical activity activity.
  5. There is no risk of developing heart failure. The method eliminates the need for a pacemaker, since it prevents heart rhythm disturbances.

Technical features of the Ozaki operation

The procedure consists of several key stages that ensure successful replacement of the aortic valve: 1. Preparation of the pericardium. The patient’s heart membrane (pericardium) is used as a basis for new valve cusps. A small piece of tissue measuring about 7×8 cm is removed. This flap is thoroughly cleaned and placed in a special solution that strengthens the structure while maintaining its elasticity. 2. Formation of cusps. Based on the anatomical parameters of the patient, new cusps are cut out of the treated pericardium. They perfectly match the individual characteristics of the body, which ensures their long-term functionality. 3. Implantation. The finished cusps are carefully fixed on the patient’s preserved valve ring. This allows for full restoration of the aortic valve and maintenance of normal blood flow.


Recovery and prognosis

After the operation, patients undergo a standard rehabilitation period. Initially, inpatient observation is required, where doctors monitor the condition and monitor the restoration of heart function. This is followed by outpatient rehabilitation with a gradual increase in physical activity. The use of the patient’s own tissues significantly reduces the likelihood of complications, including the risk of rejection. The new valve demonstrates high efficiency, providing the patient with a full life without the need for lifelong blood thinning drugs.


Why is the Ozaki method a revolution in cardiac surgery?

The Ozaki operation is considered a modern and safe solution for replacing the aortic valve. This approach offers patients not only physical health, but also psychological comfort, since there is no need for repeated surgeries and long-term drug treatment. Thanks to its effectiveness, the Ozaki method gives patients the opportunity to lead an active lifestyle without the restrictions imposed by traditional treatment methods.

Who performs the Ozaki method surgery?

Professor Cem Alhan is a leading cardiac surgeon in Istanbul with many years of experience in performing such operations. His professionalism allows him to restore health and activity to patients, freeing them from the limitations caused by aortic valve defects.

How to get a consultation?

You can sign up for a free online consultation with Professor Alhan by leaving a request on our website. We will help you organize a meeting and choose a convenient time. Take care of your heart – you only have one!

 

Baskent University Istanbul Hospital

Baskent University Istanbul Hospital

3
million patients per year
90%
organ transplant success rate

Başkent University Istanbul Hospital is a progressive medical complex that aims to provide the highest quality medical services in a comfortable environment. The clinic is part of the prestigious Turkish network of university hospitals Başkent Healthcare Group, whose achievements are known not only in the country but also far beyond its borders – in the international medical arena.

Başkent University Istanbul Hospital is a progressive medical complex that aims to provide the highest quality medical services in a comfortable environment. The clinic is part of the prestigious Turkish network of university hospitals Başkent Healthcare Group, whose achievements are known not only in the country but also far beyond its borders – in the international medical arena. Başkent University Istanbul Hospital opened its doors in 2007. The clinic is equipped with the most modern equipment, the total area of ​​the complex is 13,000 sq.m, which houses 196 equipped modern hospital beds. The clinic also consists of:

  • 21-bed Palliative Care Center
  • Intensive care for newborns (12 beds)
  • 10-bed resuscitation intensive care
  • 7-bed coronary intensive care

In addition, operating rooms, intensive care, floor ventilation, generator performance and other technical rooms are under constant control in the automation control center to maintain the operation of uninterruptible power supplies, thus ensuring the operation of the hospital in the event of a power failure.

See More
Health Group Medicana (MEDICANA)

Health Group Medicana (MEDICANA)

2,5
million patients per year
14
hospitals

The clinic started its work in 1992, thanks to its experienced staff and the highest level of service, the clinic has achieved tremendous success in the healthcare sector. Medicana Health Group provides healthcare services to its patients in 14 hospitals and 7 regions of Turkey, namely Istanbul, Ankara, Izmir, Konya, Samsun, Sivas and Bursa. Oncology, oncological surgery, organ transplantation, bone marrow transplantation, neurosurgery, IVF, genetics, cardiovascular surgery, orthopedics and traumatology, obesity surgery are some of the areas of Medicana Health Group. Medicana Health Group, a multidisciplinary clinic with its experts, experienced doctors, nurses and medical workers.

See More
Memorial Bahcelievler Hospital

Memorial Bahcelievler Hospital

1,6
million patients per year
15
operating

Memorial Bahçelievler Hospital is a multidisciplinary hospital in Istanbul, part of the Memorial medical center network. The network has 11 hospitals, 3 medical centers and 700 staff members. It is equipped with high-tech equipment, the most advanced systems in the treatment of cancer and cardiac diseases. The clinic has one of the strongest departments for general and robotic surgery, where the most complex operations are successfully performed.

See More
Memorial Ataşehir Istanbul

Memorial Ataşehir Istanbul

93.5
kidney transplant success
1227
directions

Memorial Ataşehir Hospital is a multidisciplinary hospital in Istanbul. It is part of the largest medical network Memorial. It is equipped with high-tech equipment, the most advanced cancer treatment systems: the new generation Elekta Versa HD SIGNATURE irradiation, robotic surgery, X-ray imaging systems, one of the radiological imaging systems 3 Tesla MR technology, angiographic units for vascular examination, and the clinic also specializes in neurosurgery, cardiac surgery, reproductive medicine and IVF centers, hematology, breast health are popular. Memorial Ataşehir Hospital provides assistance in various areas to patients from all over the world.

See More

Similar articles

More articles
Resuscitation and Safety in Turkish Clinics: What International Patients Need to Know
09.10.26

Resuscitation and Safety in Turkish Clinics: ...

Reading time: 7 minutes | When choosing medical treatment abroad, patients usually compare doctors, clinics, surgical costs, reviews and accommodation arrangements. However, there is another question that is particularly important to ask before undergoing surgery: What will happen if a serious complication occurs during or after the operation? Even elective surgery cannot be completely free of medical risks. Depending on the patient’s condition and the type of procedure, complications may include bleeding, cardiac arrhythmias, breathing problems, reactions to anaesthesia, infections, thromboembolic complications and other unexpected situations. This does not mean that a complication will nec
Read
Medical Tourism in Türkiye: Why Do Patients from Around the World Choose Türkiye for Medical Treatment?
05.10.26

Medical Tourism in Türkiye: Why Do Patients f...

Reading time: 5 minutes | Medical tourism is the practice of travelling to another country to receive medical care. People choose to seek treatment abroad for a variety of reasons, including the cost of care, access to specific medical services, the opportunity to consult a specialist with relevant expertise, the quality of a clinic’s facilities, waiting times, or the desire to be treated by a doctor experienced in a particular procedure. Over the past few decades, Türkiye has developed a significant international healthcare sector. According to data published by USHAŞ (International Health Services Inc.), based on statistics from the Turkish Statistical Institute (TurkStat / TÜİK), 1,398,58
Read
Turkey or the USA: Where Is It More Cost-Effective to Have a Full Medical Check-Up?
05.09.26

Turkey or the USA: Where Is It More Cost-Effe...

Reading time: 3 minutes | A regular medical check-up is an opportunity to assess your overall health, even if you have no symptoms or specific concerns. However, the process can look very different from one country to another. Costs, the organisation of examinations, access to specialists and the time required can all vary significantly. For patients from the USA, Turkey is becoming an attractive option for planned medical diagnostics, especially for those paying for healthcare privately and looking to complete a comprehensive check-up within a short period of time. One such example is Olya, who travelled from Miami to Istanbul specifically to have a medical check-up organised through Global
Read
Cancer Screening in Turkey at Memorial Hospitals: Programs, Costs and What to Expect
05.08.26

Cancer Screening in Turkey at Memorial Hospit...

Cancer Screening in Turkey: Why Early Detection Matters Cancer remains one of the leading health concerns worldwide. Many types of cancer can develop without noticeable symptoms in their early stages, making preventive screening an important part of maintaining long-term health. Regular cancer screening helps assess potential risk factors, detect certain abnormalities early, and support timely medical decision-making. Globalmedik assists patients from the United States, Canada, and other countries in arranging comprehensive cancer screening (Oncology Check-Up) programs at leading hospitals in Turkey, including the Memorial Hospitals Group. Modern oncology screening programs are designed to h
Read
Comprehensive Medical Check-Up in Turkey: What You Need to Know Before Your Trip
03.08.26

Comprehensive Medical Check-Up in Turkey: Wha...

Why Are Medical Clinics in Turkey So Popular? Taking care of your health means more than visiting a doctor when symptoms appear. Regular preventive medical check-ups help identify potential health concerns at an early stage, monitor chronic conditions, and provide valuable information about your overall well-being. Early detection can improve treatment planning and support better long-term health outcomes. Unfortunately, many people postpone routine health screenings because the process can be time-consuming and inconvenient. Multiple appointments, different diagnostic centers, long waiting times, and fragmented care often discourage patients from undergoing regular examinations. A comprehen
Read
More articles